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Notify people that: Tramadol Hydrochloride Extended-Release is for oral use only and should be swallowed full. The capsule shouldn't be chewed, dissolved, crushed or split. Tramadol Hydrochloride Extended-Launch could lead to seizures and/or serotonin syndrome with concomitant utilization of serotonergic agents (including SRIs, NRIs, and triptans)